nanopartikel-teknik i samband med den nasala läkemedelsleveransen i hjärnan vid Herantis CDNF-behandlingar för Parkinsons sjukdom.

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18 May 2020

Herantis Pharma Plc is an innovative drug development company looking to break the boundaries of standard therapeutic approaches. Our regenerative medicine drug candidates include i. CDNF biological therapy that acts on the proteostatic mechanisms of disease for the treatment of Parkinson’s disease and other neurodegenerative diseases, and ii. The intranasal administration route of CDNF is an important program for Herantis to maximize the chances of success for CDNF in brain disorders. We are excited to evaluate the Nanoform technology as part of this initiative; and we look forward to what this partnership will bring.

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Instead of committing significant resources towards a Phase II study involving an implanted surgical device the company has, at this stage, resolved to pursue more patient-friendly modes of delivery that do not require the need for a surgical device. Based on internationally recognized science, Herantis’ drug development pipeline targets breakthroughs in diseases with unmet clinical need. We aim to develop our products through clinical proof-of-concept and, where considered appropriate, to partner with large pharmaceutical or biotech companies for late-stage development and commercialization. 2021-03-10 Herantis Pharma Oyj: Herantis Pharma to focus on CDNF and xCDNF programs 2021-03-25 07:00 · Cision Herantis Pharma Oyj: Herantis Pharma Published the Annual Report for the Financial Year 2020 Herantis Pharma Plc (“Herantis” or “Company”) announced today an update on the development of its non-invasive next generation CDNF, or xCDNF. The xCDNF development program was initiated in July 2018 to develop cell-protecting molecules that penetrate the blood-brain barrier, building on the Company’s cumulated expertise on CDNF, Herantis’ lead compound in Parkinson disease. 2019-09-26 Herantis Pharma Plc. Company release, Inside Information 29 March 2021 at 9:00 PM EET. Herantis Pharma Plc ("Herantis or the Company"), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis' CDNF and xCDNF assets and to commence seeking out 2017-10-02 Thus, Herantis has decided to evaluate the best path forward with its clinical stage asset CDNF, using alternative administration methods. Instead of committing significant resources towards a Phase II study involving an implanted surgical device the company has, at this stage, resolved to pursue more patient-friendly modes of delivery that do not require the need for a surgical device.

It stopped, and to some extent reversed, the progression of the disease. CDNF - a biological protein - is Herantis' lead program and a clinical stage asset; and xCDNF - a synthetic peptide version of CDNF - is Herantis' follow-on program. Both CDNF and xCDNF have, via their multimodal mechanism of action, the potential improves neuronal survival and to stop the progression of Parkinson's and other neurodegenerative

CDNF is a natural protein that occurs naturally in the body whose natural role is to protect neurons by balancing and supporting proteostasis, thereby preventing and counteracting disease generating mechanisms. Herantis is taking this natural ability and harnessing it as a treatment for neurodegenerative disease.

Herantis Pharma är noterat på Nasdaq First North i både Stockholm och Helsingfors. CDNF, or Cerebral Dopamine Neurotrophic Factor, is an endoplasmic reticulum located and secreted protein with neuroprotective and neurorestorative properties, patented worldwide by Herantis.

17 Dec 2020 "We are delighted to support Herantis Pharma in their development programs in CDNF and latest generation xCDNF molecules. Completing this 

2020-01-03 Herantis Pharma Oyj: Herantis Pharma to focus on CDNF and xCDNF programs 2021-03-25 07:00 · Cision Herantis Pharma Oyj: Herantis Pharma on julkaissut vuoden 2020 vuosikertomuksen 1 day ago Herantis Pharma Plc. ClinicalTrials.gov Identifier: NCT03295786 Other Study ID Numbers: HP-CD-CL-2002 2015-004175-73 ( EudraCT Number ) First Posted: September 28, 2017 Key Record Dates: Last Update Posted: January 13, 2020 Last Verified: January … Topline results of Phase 1-2 CDNF trial. Posted in Industry News on 7th Mar 2020. Herantis Pharma Plc announces topline results of Phase 1-2 CDNF trial. Topline analysis confirms positive safety and tolerability of CDNF in advanced-stage Parkinson’s disease patients, with encouraging biological responses as measured by PET imaging in some patients.

Herantis cdnf

CDNF for Parkinson's disease, Lymfactin for secondary lymphedema, CDNF for Amyotrophic lateral sclerosis and  Herantis Pharma Oyj: Herantis Pharma to focus on CDNF and xCDNF programs. 29.3.2021 Digitalous · Legendaarisesta scifi-tähdestä tehtiin  (CDNF) infusion till patienter med PS av måttlig svårighetsgrad. Studien har fått EU stöd och sponsorn är Herantis Pharma (https://treater.eu; ClinicalTrials. gov  Herantis Pharma är ett finländskt läkemedelsutvecklingsbolag som i kliniska studier – CDNF mot Parkinsons och Lymfactin mot lymfödem. Herantis Pharma meddelar att toplinedata från bolagets fas I-II-studie med kandidaten CDNF för behandling av patienter med Parkinsons  2020-08-27 08:00:00 Herantis Pharma Herantis Pharma Oyj: Herantiksen CDNF on turvallinen ja hyvin siedetty Vaiheen 1-2 tutkimuksessa 12  6 April, 17:00.
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Herantis cdnf

Based on this discovery, Herantis has secured worldwide patents for CDNF and launched a drug development program. Herantis Pharma Plc. Company release, Inside Information. 29 March 2021 at 9:00 PM EET. Herantis Pharma Plc (“Herantis or the Company”), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis’ CDNF and xCDNF assets and to commence seeking 2020-02-25 Herantis Pharma has announced that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson’s disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease. Herantis Pharma Plc. Company release, Inside Information .

2020-01-22 2020-04-20 Herantis Pharma is a Finnish innovative biopharmaceutical company focusing on regenerative medicines for unmet needs. Key assets include CDNF for Parkinson’s disease and Lymfactin for breast cancer associated lymphedema. 2021-03-11 Herantis Pharma Plc Company release, insider information 25 February 2020 at 9:00 AM Eastern European Time. Herantis Pharma Plc ("Herantis" or "Company") announced today the topline results from the ongoing Phase 1-2 clinical trial examining Herantis' proprietary neuroprotective factor and novel drug candidate, CDNF, in patients with Parkinson Herantis is currently exploring other less invasive, more patient-friendly ways to deliver CDNF to patients.
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Herantis also announced today the next step for the CDNF program with the planning of a Phase 2 study with a longer treatment period that will assess the efficacy of CDNF in earlier-stage, well-characterized Parkinson’s patients.

Instead of committing significant resources towards a Phase II study involving an implanted surgical device the company has, at this stage, resolved to pursue more patient-friendly modes of delivery that do not require the need for a surgical device. Based on internationally recognized science, Herantis’ drug development pipeline targets breakthroughs in diseases with unmet clinical need. We aim to develop our products through clinical proof-of-concept and, where considered appropriate, to partner with large pharmaceutical or biotech companies for late-stage development and commercialization. 2021-03-10 Herantis Pharma Oyj: Herantis Pharma to focus on CDNF and xCDNF programs 2021-03-25 07:00 · Cision Herantis Pharma Oyj: Herantis Pharma Published the Annual Report for the Financial Year 2020 Herantis Pharma Plc (“Herantis” or “Company”) announced today an update on the development of its non-invasive next generation CDNF, or xCDNF.


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Based on internationally recognized science, Herantis’ drug development pipeline targets breakthroughs in diseases with unmet clinical need. We aim to develop our products through clinical proof-of-concept and, where considered appropriate, to partner with large pharmaceutical or biotech companies for late-stage development and commercialization.

Herantis Pharma has announced that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson’s disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease. Based on internationally recognized science, Herantis’ drug development pipeline targets breakthroughs in diseases with unmet clinical need. We aim to develop our products through clinical proof-of-concept and, where considered appropriate, to partner with large pharmaceutical or biotech companies for late-stage development and commercialization. Herantis Pharma Plc is an innovative drug development company looking to break the boundaries of standard therapeutic approaches. Our regenerative medicine drug candidates include i. CDNF biological therapy that acts on the proteostatic mechanisms of disease for the treatment of Parkinson’s disease and other neurodegenerative diseases, and ii. Herantis Pharma Plc is an innovative drug development company looking to break the boundaries of standard therapeutic approaches.