2011-11-11 · Pleiotropic genes were characterized by comparing the length of pleiotropic genes (in kilobases) to the length of nonpleiotropic genes with Ensembl. We conducted an analysis of biological processes that the genes were associated with (by using Gene Ontology [GO] terms 21 via GOrilla 22 , 23 ) to investigate evidence for enrichment of biological processes among pleiotropic genes.

other genes in the system. Contrarily, selection on the highly pleiotropic POMC gene, which orchestrates the activation of the different melanocortin receptors, 

https://doi.org/10.1351/goldbook.P04695. A gene affecting more than one (apparently unrelated) characteristic of the. phenotype . Source: S1), suggesting a pleiotropic effect of this gene on these traits. Mapping QTL for Seed Protein Content and Yield Components. To dissect the genetic control of  Genes showing pleiotropy produce a single polypeptide just like other non pleiotropic History • The term "pleiotropie" was coined in a 1910 by Festschrift • The  The phenomenon in which a single gene has multiple effects is called pleiotropy. This means a single gene often influences more than one phenotypic characters.

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: producing more than one effect especially : having multiple phenotypic expressions a pleiotropic gene. A phenomenon in which multiple and diverse phenotypic outcomes are influenced by a single gene (or single gene product.) Svenska synonymer. Engelska synonymer. Inga svenska synonymer finns. Pleiotropy, Genetic — Genetic Pleiotropism — Pleiotropism, Genetic — Pleiotropic Gene — Gene, Pleiotropic — Genes, Pleiotropic — Pleiotropic Genes. 2015-10-09 · Introduction • Defination- Pleiotropism is defined as when one gene influences multiple, unrelated phenotypic traits • Pleiotropy describes the genetic effect of a single gene on multiple phenotypic traits • Mutation in a pleiotropic gene may have an effect on some or all traits • Mechanism of pleiotropy in most cases is the effect of a gene on metabolic pathways that contribute to different phenotypes In genetics, pleiotropy is the property in which a gene can affect more than one function or phenotype in an organism.

From a  Pleiotropy is the phenomenon whereby a single gene has multiple consequences in numerous tissues. Pleiotropic effects stem from both normal and mutated  The multiple phenotypic effect of a single gene is called pleiotropism.

Pleiotropy refers to the phenomenon in which a single gene controls several distinct, and seemingly unrelated, phenotypic effects. A classic example of pleiotropy is the human disease PKU (phenylketonuria).

An ATP-binding cassette pleiotropic drug transporter protein is  This finding implies that the SNP has strong pleiotropic effects on adiposity and adiposity-independent pathological pathways that leads to increased mortality. a variety of polypeptides which have pleiotropic effects on cell differentiation, The regulation of reporter gene transcription by growth hormone in cultured  BRMS1: A Functional Gene Regulation. Among them, miR-146a and b are pleiotropic regulators of tumorigenesis.

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pleiotropic gene synonyms, pleiotropic gene pronunciation, pleiotropic gene translation, English dictionary definition of pleiotropic gene. also plei·ot·ro·pism n.

fermenting (SWI/SNF) complex, a set of pleiotropic transactivators that counteract  Interestingly, genetic variants affecting MHCII expression levels are James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L. Pleiotropic role for MYCN in  Significant pleiotropic effects were identified for mutations in four Cer genes of which one is known to participate in wax biosynthesis. 27 Cer leaf genes and  This finding implies that the SNP has strong pleiotropic effects on adiposity and adiposity-independent pathological pathways that leads to increased mortality. We here performed gene expression analysis in order to characterize the cellular These pleiotropic features make iron chelators an attractive option for the  Pleiotropy (from Greek πλείων pleion, "more", and τρόπος tropos, "way") occurs when one gene influences two or more seemingly unrelated phenotypic traits. Such a gene that exhibits multiple phenotypic expression is called a pleiotropic gene. Pleiotropy is the expression of multiple traits by a single gene.
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7.5 K. A pleiotropic gene in humans is.

They are Pleiotropic definition, responsible for or affecting more than one phenotypic characteristic: Scientists are trying to determine if the various effects of pleiotropic genes are sensitive in different ways to different environmental influences.
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Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits. Such a gene that exhibits multiple phenotypic expression is called a pleiotropic gene. Mutation in a pleiotropic gene may have an effect on several traits simultaneously, due to the gene coding for a product used by a myriad of cells or different targets that have the same signaling function. Pleiotropy can arise from several distinct but potentially overlapping mechanisms, such as gene pleiotropy, deve

What are synonyms for pleiotropic gene? All the 11 pleiotropic genes described above are also analyzed here and five (i.e., RSG1, LRP10, RBM23, WNT9B, and GOSR2) are replicated (Supplementary Table 16). Functional Analyses for Pleiotropic Genes.